GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | BMPR1A | chr10:88516396-88684944:+ | -0.25 | -6.49 | 2.21E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | C10orf47 | chr10:11865397-11914274:+ | -0.22 | -5.9 | 6.99E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.29 | 7.02E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | EFNB2 | chr13:107142098-107187337:- | -0.26 | -6.15 | 1.64E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.97 | 1.05E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | EPDR1 | chr7:37960163-37991539:+ | 0.33 | 7.3 | 1.18E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.94 | 5.35E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -5.93 | 5.85E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.7 | 5.46E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925488 | chr9:100546391 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.17 | 1.49E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.28 | 7.82E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | CENPJ | chr13:25456414-25497085:- | 0.22 | 5.9 | 6.96E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.15 | 1.69E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.89 | 1.77E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs925489 | chr9:100546600 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.09 | 4.78E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |